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Is weight loss as simple as calories in, calories out? In the end, it’s your gut microbes and leftovers that make your calories count

  • Written by Christopher Damman, Associate Professor of Gastroenterology, School of Medicine, University of Washington
Is weight loss as simple as calories in, calories out? In the end, it’s your gut microbes and leftovers that make your calories countTwo foods may have the same number of calories, but other food factors and your microbes influence which calories your body uses more of.Martin Barraud/OJO Images via Getty Images

Is the adage “calories in, calories out” true? The short answer is yes, but the full story is more nuanced.

From the moment food touches your tongue to the...

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